1 If you use a USB cable, not WIN7 and above, you need to install the driver. And select USB communication in the communication settings.
2 If you use serial communication, you can ensure that the line hardware is no problem. Set the correct port to make sure the port is not occupied. And from the system you can see which COM port your converter uses, do not try. If there is no problem, you can try to lower the baud rate. Sometimes the line quality is not good and high-speed communication will not communicate.